Institute of Post Graduate Medical Education & Research

A Center of Excellence in Medical Education and Research

Services

Multi-Disciplinary Research Unit (MRU), I.P.G.M.E & R, Kolkata

Department of Health Research (DHR), Govt. of India approved the establishment of a Multidisciplinary Research Unit in I.P.G.M.E&R in 2016 as part of a national scheme to establish such units in State Govt. Medical Colleges with a view to create a dedicated infrastructure for research with special focus on Non-Communicable Diseases (NCDs). The Unit is located on the 5th floor, Academic Building, I.P.G.M.E&R.

Objectives of the MRU:

  • Encourage and strengthen development of an ecosystem for undertaking research in medical colleges.
  • To improve the overall health status of the population by creating evidence-based application of diagnostic procedures/processes/methods.

MRU Core Committee:

Prof. GK Dhali, Professor and Head, School of Digestive & Liver Diseases Chairperson
Prof. Manimoy Bandyopadhyay, Director, IPGME&R Member
Prof. Simanti Datta, Professor, Centre for Liver Research, School of Digestive & Liver Diseases Nodal Officer
Dr. Pradyut Sinha Mahapatra, Associate Professor, Dept. of Rheumatology & Clinical Immunology Member
Prof. Pradip Mukhopadhyay, Professor, Dept. of Endocrinology and Metabolism Member
Prof. Kakali Basu Roy, Professor, Dept. of Physiology Member

Local Research Advisory Committee

Prof. Raghunath Misra, Principal IQ City Medical College and Hospital, Former Principal, Calcutta Medical College Chairperson
Prof. Manimoy Bandyopadhyay, Director, IPGME&R, Kolkata Member (Rep. of State Govt.)
Prof. Simanti Datta, Professor, Centre for Liver Research, School of Digestive and Liver Diseases, IPGME&R, Kolkata Nodal Officer, MRU
Prof. Aniruddha Neogi, Special Secretary, Dept. of Health & Family Welfare, Govt. of West Bengal Member (Rep. of State Govt.)
Dr. Partha Chakrabarti, Senior Principal Scientist, Indian Institute of Chemical Biology, Kolkata Member
Dr. Santasabuj Das, Scientist-F, ICMR-National Institute of Cholera and Enteric Diseases (NICED), Kolkata Member (ICMR Rep)
Prof. Indranil Chakraborty, Professor, Dept. of Biochemistry, College of Medicine and Sagar Dutta Hospital, Kolkata Member
Dr. Pradyot Sinha Mahapatra, Associate Professor, Dept. of Rheumatology and Clinical Immunology, IPGME&R, Kolkata Member
Prof. Kakali Basu Roy, Professor, Dept. of Physiology, IPGME&R, Kolkata Ex-VC, West Bengal University of Health Sciences Member
Prof. Gopal Krishna Dhali, Professor & Head, School of Digestive and Liver Diseases, IPGME&R, SSKM Hospital, Kolkata Member
Prof. Pradip Mukhopadhyay, Professor, Dept. of Endocrinology and Metabolism, IPGME&R, Kolkata Member

Staff structure of MRU, I.P.G.M.E&R:

Prof. Simanti Datta,
Professor, Centre for Liver Research,
School of Digestive and Liver Diseases,
Nodal Officer,
MRU, IPGME&R, Kolkata
Dr. Payel Bhattacharjee
Research Scientist-II
(Scientist C)
Dr. Bidhan Chandra Chakraborty
Research Scientist-I
(Scientist B)
Mr. Jaydeep Banerjee
Laboratory Technician
Mrs. Susmita Maity Sasmal
Laboratory Technician
Mr. Abhijit Chowdhury
Laboratory Assistant

Facilities available:

Immunology Lab

  • Bench Top Flow Cytometer
  • Electrophoresis and blotting apparatus (horizontal and vertical)
  • Vortex Shaker
  • 4°C Refrigerator
  • ELISA Reader and Washer

Cell Biology Lab & Tissue Culture Lab

  • Portable Refrigerated Micro centrifuge
  • Double beam UV- visible Spectrophotometer
  • Fully Automated Fluorescent Imaging System (EVOS FL Auto)
  • Fluorescent Imaging System (Leica Thunder Imager)
  • -20°C refrigerator
  • -80°C refrigerator
  • Refrigerated Centrifuge (table top)
  • Biosafety Cabinets
  • CO2 incubator
  • Microscope (inverted)
  • Centrifuge
  • Vortex Shaker

For Molecular Biology Lab

  • Low Volume Spectrophotometer (NanoDrop One C)
  • Real Time PCR & Qualitative PCR
  • Multi-block PCR Thermal Cyclers
  • Droplet Digital PCR
  • Chemi Doc Imaging System
  • Laminar Air Flow
  • 40°C refrigerator
  • 37°C bacterial incubator with shakers
  • Water bath
  • Non Refrigerated Microcentrifuge.

Faculty members of the IPGME&R in-charge of the different instruments of MRU

Sl No. Name Designation with Department Name of the Instrument
1 Dr. Prodyot Sinha Mahapatra Associate Professor, Dept. of Rheumatology, IPGME&R BD FACS Verse flow cytometer
2 Prof. Soma Banerjee Professor, Centre for Liver Research, IPGME&R BioRad Droplet Digital PCR
3 Prof. Keya Basu Professor, Dept. of Pathology, IPGME&R EVOS Automated Florescent Microscope
4 Prof. Simanti Datta Professor, Centre for Liver Research and Nodal Officer, MRU, IPGME&R Cell Culture Facilities

Project Coordinator:

1. Dr. Payel Bhattacharjee, Research Scientist-II (Scientist C), MRU, IPGME&R

2. Dr. Bidhan Chakraborty, Research Scientist-I (Scientist B), MRU, IPGME&R

Research in progress:

  • Research concept proposals are invited from faculty of IPGME&R to undertake projects (1-2 years duration) focussed on addressing the health needs of West Bengal, and utilizing the equipment procured by the MRU.
  • A concept proposal of 3-5 pages (max. 3000 words) and CV of the PI to be submitted during the call.
  • Each Concept proposal is initially screened by the MRU Core Committee.
  • Final recommendation of the proposal is made by the Local Research Advisory Committee based on the review report.

Ongoing Projects in MRU

Proposal No and Project Title Name of PI & Department
An altered ratio of CD4+ and CD8+ T lymphocytes in Cervical Cancer tissue and Peripheral blood as a predictor of prognostic outcome – A clinicopathological study. Prof. Diptimay Das
Professor, Dept. of Radiotherapy
Genetic polymorphisms of Methylene Tetrahydrofolate Reductase (MTHFR) [rs1801133 (C677T) and rs1801131 (A1298C)] and risk of ischemic stroke in a Eastern Indian Population. Prof. Nandini Chatterjee
Professor, Dept. of Medicine
Evaluation the antifungal effect of safe, biocompatible serum capped silver nanoparticle on clinically important Candida isolates Dr. Nupur Pal
Associate Professor, Dept. of Microbiology
The changing trends in the etiological and clinic-radiological profiles and long-term outcomes of Acute Encephalitis Syndrome among children below 15 years of age- a prospective bicentric study. Prof. Biman Kanti Ray
Professor, Neuromedicine, Bangur Institute of Neurosciences
Etiological study of Neonatal & Infantile Cholestasis Syndrome (with a focus on MMP-7 as a biomarker for biliary atresia, definitive diagnosis of normal GGT cholestasis and treatable metabolic liver diseases). Dr. Gautam Ray
Assistant Professor, School of Digestive and Liver Diseases
To explore the role of antimicrobial peptides in initiation and progression of Ulcerative Colitis Dr. Arko Banerjee
Associate Professor, School of Digestive and Liver Diseases

Project Completed

Proposal No and Project Title Name of PI & Department
MRU/PG/14/2017
Role of Immunofluorescence antigen mapping in diagnosis of Epidermolysis Bullosa- a rare genetic blistering disorder.
Prof. Keya Basu
Professor, Dept. of Pathology
MRU/PG/08/2017
Establishment and characterization of human renal proximal tubular cell for determining expression f SGLT2 amongst Type II diabetes
Prof. Sujoy Ghosh
Professor, Dept. of Endocrinology & Metabolism
MRU/PG/15/2017
Expression of DNA mismatch repair proteins in primary and metastatic carcinoma gall bladder
Dr. Ranajoy Ghosh
Assistant Professor, School of Digestive & Liver Diseases
MRU/PG/01/2017
Role of TSIX and antisense TSIX in modulation of fibrotic pathway in pathogenesis of Systemic Sclerosis
Dr. Pradyot Sinha Mahapatra
Associate Professor, Dept. of Rheumatology & Clinical Immunology
MRU/PG/10/2017
Alterations in neutrophils extracellular traps in patient with Acute on Chronic Liver Failure (ACLF)
Dr. Sk Mahiuddin Ahammed
Assistant Professor, Dept. of Hepatology, School of Digestive and Liver Diseases
MRU/PG/18/2017
Identification of potential biomarkers for disease monitoring in asthma
Dr. Sujoy Ghosh
Assistant Professor, Dept. of Respiratory Medicine
MRU/PG/10/2018
M type phospholipaseA2 receptor as target antigen in idiopathic membranous nephropathy
Dr. Moumita Sengupta
Assistant Professor Dept. of Pathology
MRU/PG/01/2018
Insights into B cell immunity in chronic hepatitis B virus infection
Prof. Simanti Datta
Professor, Centre for Liver Research, School of Digestive and Liver Diseases
MRU/PG/02/2018
Effect of Rituximab on B cell subpopulations in the treatment of scleroderma lung disease
Dr. Geetabali Sircar
Assistant Professor, Department of Rheumatology & Clinical Immunology
MRU/PG/03/2018
Role of quantitative monitoring of B cells in evaluating safety and effectiveness of Rituximab in a tertiary care hospital
Dr. Gairik Sengupta
Associate Professor, Dept. of Pharmacology
MRU/PG/10/2018
Role of Dyslipidemia in Pathogenesis of Diabetic Retinopathy
Prof. Subhankar Chowdhury
Professor, Dept. of Endocrinology
MRU/PG/01/2019
To explore the role of antimicrobial peptides in initiation and progression of Ulcerative Colitis
Dr. Arka Banerjee
Associate Professor, School of Digestive and Liver Diseases
MRU/PG/06/2019
Study of differential behaviour of visceral and subcutaneous adipocytes and its association with the biochemical markers of macrovascular risk factors in obese and non-obese diabetic individuals
Dr. Rana Bhattacharjee
Assistant. Professor, Dept. of Endocrinology & Metabolism
MRU/PG/07/2019
Assessment of Complement Activation in IgA Nephropathy: A move towards better prognostic and Therapeutic Precision
Prof. Keya Basu
Professor, Dept. of Pathology
MRU/PG/09/2019
Congenital and developmental ocular disorder in paediatric patients and their association with genetic variants in a tertiary care hospital of Eastern India
Dr. Smiti Srivastava
Associate Professor, Dept. of Opthalmology
MRU/PG/10/2019
Role of immune signature in recurrent urinary bladder Carcinoma
Prof. Dilip Kumar Pal
Professor and Head, Dept. of Urology
MRU/PG/12/2019
Ependymomas – Single institutional cohort with histopathological, immunohistochemical, molecular characterization and its prognostic utility
Dr. Mou Das
Associate Professor, Dept. of Pathology
MRU/PG/15/2019
Genotype and allele frequency and of CYP2C19 in ischaemic heart disease patients on clopidogrel
Dr. Nafisha Yasmin
Assistant Professor, Dept. of Pharmacology
MRU/PG/20/2019
PCR based methods to detect level of donor-derived cell-free DNA for identification of acute rejection in kidney transplantation: a pilot study
Prof. Arpita Roy Chowdhury
Professor, Dept. of Nephrology

Extramural Grants received during last 5 Years as on 1st January 2015:

Dept. of Medicine

Name of faculty Research project Grant giving agency Year of sanction with duration Amount sanctioned
(in lakhs)
Dr Sk Nasim, Assistant Professor Genetic polymorphisms determining telomere length and their association with non-CML Myeloproliferative Neoplasms – a cross sectional analytical multi-centric study from Eastern Indian Population. ICMR, Govt. of India 2023-26 25,73,228

Dept. of Pathology

Name of faculty Research project Grant giving agency Year of sanction with duration Amount sanctioned
(in lakhs)
Prof. Madhumita Mukhopadhyay Role of Calretinin Staining in Hirschsprung’s Disease in  Infants DST (West Bengal) 2013-16 12,43,000
Prof. Chhanda Dutta IDH expression in gliomas DBT (West Bengal) 2015-18 28,00,000

Dept. of Biochemistry

Name of faculty Research project Grant giving agency Year of sanction with duration Amount sanctioned
(in lakhs)
Prof. Sasanka Chakrabarti Role of a-synuclein and parkin in dopamine toxicity on SHSY5Y cells: implications for sporadic Parkinson's Disease. DST, Govt. of India 2013-16 39,56,000/-
Prof. Sasanka Chakrabarti Identification of Molecular Links between amyloid precursor protein (APP) metabolism and disease related biomarkers in an experimental model with SHSY5Y cells DBT, Govt. of India 2013-16 67,01700/-
Prof. Sasanka Chakrabarti Elucidation of the mechanisms of dopamine induced mitochondrial damage and search for neuroprotective agents: an experimental study with rat brain mitochondria and PC-12cells with implications in Parkinson's disease. BRNS 2009-12 17,00, 000/-
Prof. Sasanka Chakrabarti Elucidation of different mechanisms of mitochondrial dysfunction in adipose tissue of type 2 diabetes patients with or without obesity. CSIR, Govt. of India 2009-12 20,00000/-
Prof. Sasanka Chakrabarti Elucidation of different mechanisms of amyloid β protein (Aβ) toxicity in young and aged rat brain: an experimental study with brain subcellular fractions and animal models with implications in Alzheimer’s disease. DST, Govt. of India 2009-12 27,25,000

Dept. of Rheumatology & Clinical Immunology

Name of faculty Research project Grant giving agency Year of sanction with duration Amount sanctioned
(in lakhs)
Prof. Alakendu Ghosh. Epidemiological evaluation of “Low Back Pain” prevalent among different strata of people in West Bengal. W. Bengal State Health & Family Welfare Samiti   10,59,700
Prof. Alakendu Ghosh To determine the prevalence and cut-off of anti-cyclic citrullinated peptide (anti-CCP) antibody in our population DST (West Bengal)
2008-11  
2008-11 8,64,400
Prof. Alakendu Ghosh To determine the prevalence of hyperlipidemia, atherosclerosis and endothelial dysfunction in patients with early rheumatoid arthritis, and their response to therapy with disease modifying anti-rheumatic drugs (DMARDs) ICMR, Govt. of india 2009-12   15,52,750
Prof. Alakendu Ghosh / Dr. PS Mahapatra Evaluation of Immunomodulatory activity of Black Tea extract in Rheumatoid arthritis: an in vitro study of expresiion of inflammatory molecules and cytokines in synovial fluid and tissue cells of patients with Rheumatoid arthritis Tea Board   2012-15 15,20,000

Dept. of Pharmacology

Name of faculty Research project Grant giving agency Year of sanction with duration Amount sanctioned
(in lakhs)
Prof. Mitali Chatterjee ‘Evaluation of molecular markers for monitoring of Post Kala-azar Dermal Leishmaniasis (PKDL) in West Bengal’ ICMR, Govt. of India 2012-15 38.85
Prof. Mitali Chatterjee Role of IL 10 and T-regulatory cells in the Immunopathogenesis of Indian Post Kala–Azar Dermal Leishmaniasis (PKDL) CSIR, Govt. of India 2010-13 25.76
Prof. Mitali Chatterjee Therapeutic effectiveness of allylpyrocatechol (APC) in an experimental model of Arthritis DBT, Govt. of India 2012-15 49.25
Prof. Mitali Chatterjee Targeting thiol mediated anti-oxidant pathways as a potential chemotherapeutic modalities in Indian Leishmaniasis DST, Govt. of India 2010-13 20.00
Prof. Mitali Chatterjee Study of Immunological determinants at the lesional site of patients with PKDL (Indo-German collaborative grant) ICMR, Govt. of India 2010-12 5.00
Prof. Mitali Chatterjee Effectiveness of Artemisinin and its analogues as potential anti-leishmanial agents ICMR, Govt. of India 2009-12 16.36
Prof. Mitali Chatterjee Visceral leishmaniasis; identification and validation of biomarkers for antimony susceptibility / resistance in clinical isolates of leishmania donovani DBT, Govt. of India 2009-12 18.24
Prof. Mitali Chatterjee Evaluation of immunomodulatory activity of leaves of Piper betle linn. (paan) in patients with Prof. Mitali Chatterjee Rheumatoid arthritis State DST (West Bengal) 2008-11 12.23
Prof. Mitali Chatterjee Evaluation of molecular mechanisms responsible for the anti-inflammatory activity of allylpyrocatechol BRNS, DAE, Govt. of India 2009-12 17.35
Prof. Mitali Chatterjee Evaluation of plant derived compounds with immunomodulatory activity in Leishmaniasis (Indo-Brazil collaborative grant) DST, Govt. of India 2009-11 10.8
Prof. Mitali Chatterjee Funds for Infrastructure (FIST programme) DST, Govt. of India Coordinator 2005-10 60.0
Prof. Mitali Chatterjee Funds for Infrastructure (FIST programme) DST, Govt. of India, Coordinator 2010-15 83.0
Prof. Suparna Chatterjee MDR1      polymorphism (C3435T) with antitubercular drug induced hepatotoxicity in eastern Indian population RD Birla Smarak Kosh 2011-13 3.0
Prof. Suparna Chatterjee Antibiotic stewardship program and advocacy of rational antimicrobial use ICMR,
Govt. of India
2014-16 Co-Investigator
Prof. Suparna Chatterjee Preclinical Toxicological studies of Black Tea with special emphasis on iron induced toxicity Tea Board of India 2011-13 3.0
Prof. Suparna Chatterjee Effect of Probiotics on carriage of Extended Spectrum Beta Lactamase producing Enterobacteriacae in neonatal gut: A Randomized controlled trial at a Tertiary care Neonatal Intensive Care Unit DBT, Govt. of India 2012-14 Co-Investigator
Dr. Avijit Hazra Preclinical and safety studies of some proprietary herbal formulations. M/s Isha Natural & Herbal Products, Hyderabad 2011-13 4.0
Dr. Avijit Hazra Department of Science & Technology (DST), Government of West Bengal Studies of some marine flora of the Sunderbans 2012-14  2.88
Dr. Amrita Sil
&
Prof. Mitali Chatterjee
Molecular epidemiological study for evaluating role of potential host factors as markers of susceptibility of leprosy in West Bengal, India German Lepra Research Assoc. GLRA, India 2015 - 17 Co-Investigators

Dept. of Endocrinology

Name of faculty Research project Grant giving agency Duration Amount sanctioned
(in lakhs)
Prof Subhankar Chowdhury
Head of Dept.
Funds for Infrastructure
(Departmental Grant)
DST, Govt. of India 2014-19 100
Prof Subhankar Chowdhury Study of the association of adiponectin gene polymorphism and level of adiponectin with inflammation and endothelial dysfunction in type 2 diabetes subjects RSSDI,
Central Body
2 years 5.0
Prof Subhankar Chowdhury Neck circumference as a predictor of impaired glucose metabolism, body mass index, cardiovascular risk factors and metabolic syndrome in normal, pre-diabetic and diabetic population: a population based observational study DST West Bengal 3 years 7.43
Prof Subhankar Chowdhury Association of gene mutations/ polymorphisms with therapeutic efficacy of metformin in type 2 diabetes mellitus patients of West bengal, India DBT, Govt. of India 3 years 10.20
Prof Subhankar Chowdhury Role of gut microbiome in gestational diabetes mellitus DBT (W. Bengal) 3years 29.93
Prof Satinath Mukhopadhyay Molecular Mechanisms of Beta Cell Apoptosis in animal models of Diabetes. DST, Govt. of India?? 3 years 35.0
Prof Satinath Mukhopadhyay Free fatty acid induced differential regulation of CPT1 and CPT2 and its contribution to insulin resistance in skeletal muscle.  CSIR, Govt. of India 3 years Co-Investigator
Prof Satinath Mukhopadhyay Insulin resistance leads to neuronal degeneration through oxidative stress in a neural cell line. DBT, Govt. of India 3 years 67.0
Prof Satinath Mukhopadhyay Role of free fatty acids in regulation of Fetuin A and NFkB gene expression in palmitate treated adipocyte cell lines. DBT, Govt. of India 3 years  
Prof Satinath Mukhopadhyay Role of TypeI interferons in insulin resistance. CSIR, Govt. of India 3 years  
Prof Satinath Mukhopadhyay Identification of genetic markers for Indian Type2 diabetics. DBT, Govt. of India 3 years 35.0
Prof Satinath Mukhopadhyay Incretin axis and DPP-IV system in Indian Type2 diabetics RSSDI (WB) 2 years 2.0
Prof Satinath Mukhopadhyay Molecular mechanisms underlying proliferative and invasive behavior of malignant ovarian tumors CSIR, Govt. of India 3 years  
Prof Satinath Mukhopadhyay Effect of DPP4 inhibition on serum erythropoietin level in diabetic nephropathy RSSDI (WB) 2 years 1.0
Prof Satinath Mukhopadhyay Study of dipeptidyl peptidase-4 in Indian type 2 diabetes RSSDI (WB) 2 years 1.0
Prof Subhankar Chowdhury A study of the demographic and clinical profile, the genetics, incretin levels, insulin resistance and correlation of exocrine and endocrine dysfunction in patients with fibrocalcific pancreatic diabetes attending S.S.K.M Hospital, Kolkata RSSDI (WB) 2 years 1.0
Prof Subhankar Chowdhury A hospital-based study on the pattern of metabolic bone disorders in diabetic patients with chronic kidney disease with special reference to detection of adynamic bone disease in diabetic kidney disease by non-invasive assessment RSSDI (WB) 2 years 1 .0
Prof Satinath Mukhopadhyay Endocrine changes in adult patients of E-Beta thalassemia with special reference to glucose homeostasis RSSDI (WB) 2 years 1.0
Prof Subhankar Chowdhury Comparison of anthropometric parameters with special reference to wrist circumference & cardio-metabolic risk factors among treatment-naïve diabetic and non-diabetic subjects attending OPD of a tertiary care hospital in Kolkata RSSDI (WB) 2 years 1.0
Prof Satinath Mukhopadhyay Role of infrared dermal thermometry in the assessment and management of diabetic foot-a prospective observational study RSSDI (WB) 2 years 0.2
Prof Subhankar Chowdhury Evaluation of hypogonadism and its relationship with type 2 Diabetes        RSSDI (WB) 2 years 0.5
Prof Satinath Mukhopadhyay Role of selenium in type 2 diabetes RSSDI (WB) 2 years 0.5
Prof Subhankar Chowdhury Role of power Doppler in evaluation & prediction of microvascular complications of diabetes RSSDI (WB) 2 years 1.86
Prof Satinath Mukhopadhyay Comparison of TCC and PRAFO in diabetic foot ulcers RSSDI (WB) 2 years 2.00
Prof Satinath Mukhopadhyay Role of Vitamin D in Pioglitazone induced bone disease in type 2 diabetes RSSDI (WB) 2 years 2.00
Prof Subhankar Chowdhury Evaluation of neck circumference as a risk factor of coronary disease in type 2 diabetes RSSDI (WB) 2 years 1.5
Prof Satinath Mukhopadhyay Prevalence of Vitamin-D deficiency and its relation to systemic inflammatory markers and insulin resistance in prediabetic subjects RSSDI (WB) 2 years 2,00,000
Prof Satinath Mukhopadhyay Prevalence of Latent Autoimmune Diabetes of Adults (LADA) among young non obese diabetics in a Tertiary Care Diabetic Centre. RSSDI (WB) 2 years 2.0
Prof Subhankar Chowdhury Impact of hypothyroidism and thyrotoxicosis on Glycated Hemoglobin in Non – diabetic subjects. RSSDI (WB) 2 years 2.0

School of Digestive & Liver diseases

Role of mitochondrial membrane potential( m) & mitochondrial permeability transition (MPT)in the initiation of Isoniazed (INH) induced liver cell injury: an in vitro study   Dr. Amal K Santra   ICMR, Govt. of India Fellowship Programme 2009 - 2011
Evaluation of the role of CYP2e1 in the mediation of liver cell injury and alteration of hepatic stellate cell behaviour in anti- tubercular drugs induced hepatotoxicity   Dr. Amal K Santra   ICMR, Govt. of India 29,29,929/- 2010 - 2013 
Differential expression of NADPH oxidase in activation, senescence and apoptosis of hepatic stellate cells during hepatic fibrosis in mice  Dr. Amal K Santra   ICMR, Govt. of India  39,94,024/- 2012 - 2015 
A multicentric randomized controlled clinical trial of lamivudine, lamivudine and adefovir, glycyrrhizin and adefovir in HBV related decompensated cirrhosis   Dr. Abhijit Chowdhury   ICMR,
Govt. of India
24,65,960/- 2007 - 2012 
Study of Hepatitis b virus (HBV) resistance patterns in patients with chronic infection during therapy with nucleoside and nucleotide analogues Dr. Abhijit Chowdhury   ICMR, Govt. of India 36,00,000/- 2009 - 2011 
Hepatic stellate cells (hscs) activation during Isoniazid induced hepatocytes injury: an in-vitro study   Dr. Abhijit Chowdhury   ICMR, Govt. of India 31,73,983/- 2011 - 2014 
Cellular events in Hepatic stellate cell activation byIsoniazid  induced necrotic hepatocytes: An In-vitro study Dr. Abhijit Chowdhury   ICMR, Govt. of India 37,17,642/-  
Functional characterization of a new putative tumour suppressor gene, hELG1/ATAD5 and its correlation with hepatitis B virus (HBV) infection. Dr. Soma Banerjee CSIR
Govt. of India
22,94,065/- 2011 – 2014
Determination of genetic susceptibility of Alcoholic Liver Disease by studying polymorphisms of selected candidate genes in North-East Indian population. Dr. Soma Banerjee DBT
Govt. of India
31,15,000/- 2012 - 2015
Identification of Hepatitis B virus DNA integration site in liver tissue of HBV related Cirrhosis and Hepatocellular carcinoma patients to understand the mechanism of Hepatocarcinogenesis. Dr. Soma Banerjee West Bengal State DST 7,51,800/- for 1st year 2013 - 2016
Identification of signature genes for development of hepatocellular carcinoma (HCC) from liver cirrhosis (LC) for patient oriented therapy. Dr. Soma Banerjee CSIR
Govt. of India
25,39,395/- 2008 - 2011
Early molecular and genetic determinants of HBV mediated progression of fibrosis to hepatocellular carcinoma. Dr. Soma Banerjee ICMR
Govt. of India
36,09,494/- 2010 - 2013
Micro RNA mediated regulation of Liver fibrosis. Dr. Soma Banerjee ICMR
Govt. of India
33,94,454/- 2010 -2013
Biology of Hepatitis B Virus of genotype D in an integrated clinico-Virological perspective. Dr. Abhijit Chowdhury DBT
Govt. of India
18,89,800/- for 1st year 2013 - 2016
Insight into the distribution and pathogenic potential of diverse Hepatitis B Virus subgenotypes underlying different clinical outcomes of chronic infection. Dr. Simanti Datta CSIR
Govt. of India
16,84,878/- for 1st & 2nd year 2012 - 2015
Tracing the dynamics of host-virus interaction in different phases of e-antigen negative chronic hepatitis B infection. Dr. Simanti Datta ICMR
Govt. of India
31,60,943/- 2009 -2012
Study of hepatitis B virus (HBV) resistance patterns in patient with chronic infection during therapy with nucleoside and nucleotide analogues. Dr. Abhijit Chowdhury ICMR
Govt. of India
36,70,170/- 2009 -2011
Characterization of occult hepatitis B infection in Indian Patients with hepatocellular carcinoma (HCC) and in HCV/HIV carriers. Dr. Simanti Datta DST
Govt. of India
13,77,000/- 2009 -2012
Molecular Epidemiology of Hepatitis   B virus infection in Tripura. Dr. Simanti Datta ICMR, Govt. of India 38,84,963/- 2010 -2013
Assessment of Liver Diseases burden in the General population using ALT as a biomarker of Liver Disease and standardization of Normal ALT in our population Dr Abhijit Chowdhury DST, West Bengal 26,11,200/- 2011-2014